The orbital tissue expander (OTE) is an award-winning enhancement in treating congenital conditions such as anophthalmia and microphthalmia, or acquired anophthalmia from tumors or trauma. Dr. David Tse’s design consists of a flexible balloon fixed in place by a titanium plate to help mitigate the problem of permanent facial disfigurement from improper growth of the eye orbit during development. Here we’ll discuss how the OTE design plays a critical role in the treatment of these conditions.
- Anophthalmia results from one or both eyes not forming during early fetal life. Anophthalmia may be primary (complete absence of the eyeball), secondary (tiny eyes or a small amount of eye tissue) or degenerative (the eye began to develop but the development was not complete and blood supply is damaged).
- Microphthalmia is defined as an eye globe that is below the average size by 1-2 standard deviations. Microphthalmia may be simple (intact eye with shortened globe length) or complex (malformation of various parts of the eye).
Causes of anophthalmia and microphthalmia can be linked to genetic mutations, abnormal chromosomes, and environmental factors. These conditions are rare, occurring in only 1 of 10,000 live births. They account for 3-11% of child blindness. There is currently no treatment for severe anophthalmia or microphthalmia to restore vision or rebuild the eye globe. Tissue expanders and prosthetics are used to allow for growth of facial bones and to maintain a uniform appearance. Early intervention of these conditions is essential to proper anatomical development.
Conformers are placed during infancy and exchanged frequently as the child grows. A prosthesis fashioned to look like a normal eye usually replaces these conformers between the ages of one and two. Orbital implants are placed to allow for normal bone growth and to support the prosthesis. Types of orbital implants used today include the orbital tissue expander, bioceramic orbital implants, mesh-wrapped bioceramic orbital implants, silicone orbital implants, and acrylic orbital implants.
Benefits of the Orbital Tissue Expander
The orbital tissue expander’s titanium fixation plate is anchored to the lateral orbital wall. The flexible balloon implant is then expanded as the child’s eye orbit grows to help
maintain normal orbital bone growth and a symmetrical facial appearance.
The orbital tissue expander has proven to be a great improvement to previous models as it is flexible in nature and includes many benefits, including:
- Enables the ocular orbit to grow as if it were surrounding a healthy eye. This prevents facial disfigurement over time, which can occur if natural pressure on the ocular orbit is absent during development.
- Has the ability to be implanted using standard oculoplastic techniques.
- Easily inflates and deflates to omit the need for multiple surgeries as the child grows.
- Extrusion by the body is prevented by a fixed bone plate.
- Requires minimal follow-up, surgical adjustment, and intervention.
The greatest and most notable benefit of the OTE is that it can be easily increased in size as a child develops. Unlike the OTE, less popular solutions such as acrylic spheres that are not anchored to the lateral orbital rim to promote self-centering can cause complications over time. Without proper anchoring, these spheres can prolapse against the conjunctiva. Over time, issues such as this can lead to permanent facial disfigurement in the developing child.
Another great benefit of the OTE is that with patient cooperation, no general anesthesia is necessary. Patients can be locally anesthetized in order to inject the implant with fluid to maintain accurate pressure on the eye orbit. Tested at the University of Miami, the device is currently manufactured by Innovia LLC, and has been used with great success in patients with anophthalmia and microphthalmia.
The orbital tissue expander has found its place in patients with congenital anophthalmia and microphthalmia. Named in the 2010 Medical Design Excellence Awards competition, the OTE is a high-ranking medical product used both throughout the United States and also in the Middle East. Study results are overwhelmingly positive, and all patients included in these studies have had increased orbital sizes as a result of using this medical advancement.The orbital tissue expander has found its place in patients with congenital anophthalmia and microphthalmia. No infections, erosions, or implant-related issues have been documented.






